Anti-Claudin-18.2 (E1)

Anti-Claudin-18.2 [E1], Recombinant, IgG kappa, Rabbit

CloneID: E1

Antigen Long Description: The original antibody was generated by immunizing mice with CHO cells stably transfected with human claudin-18.2.

Buffer Composition: PBS only.

Uniprot Accession No.: P56856

Specificity Statement: This antibody is specific for human claudin-18.2 and does not cross react with claudin-18.1. Alterations in claudin expression can impair tight junction function, influence signaling pathways, and act as a tumor-promoting event in some epithelial cancers. Claudin 18.2 is overexpressed in various tumor type and is found to be a potentially important target in advanced gastric cancer.

Application Notes (Clone): The binding of this antibody to claudin-18.2 expressed on the surface of CHO cells was determined using flow cytometry (CN113321730).

• SKU: ABAAb03907-23.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03907-23.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Flow Cytometry
• Isotype: IgG kappa
• Host: Rabbit