CloneID: 7A1
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing mice with a phosphonate mono-ester transition state analog (TSA) of cocaine coupled through a covalent linkage to the carrier protein keyhole limpet hemocyanin (KLH).
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds to cocaine, a strong stimulant used clinically as a local analgesic and vasoconstrictor and illegally as a recreational drug.
Application Notes (Clone): This antibody catalyzes the hydrolysis of cocaine to produce nonpsychoactive metabolites ecgonine methyl ester and benzoic acid.
English
Deutsch
