CloneID: N-1
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was isolated from a phage antibody library by panning against CTLA-4.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P16410
Specificity Statement: The antibody specifically binds CTLA-4.
Application Notes (Clone): The specificity of the antibody was confirmed by ELISA analysis. The antibody had good affinity and good bioactivity, could be specifically combined with a CTLA-4 antigen, is capable of improving the activity and proliferation of T cells (CN110655579B).
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