Anti-CXCR4 (281F12)

Anti-CXCR4 [281F12], Recombinant, VHH, Camelid

CloneID: 281F12

Heavy Chain modification: His-tagged

Buffer Composition: PBS only.

Uniprot Accession No.: P61073

Specificity Statement: This antibody is specific for CXCR4.

Application Notes (Clone): The binding of the original version of this antibody (VHH) to CXCR4-expressing viral lipoparticles was characterized in an ELISA. Furthermore, it was analyzed for its ability to compete with the ligand CXCL12 (or SDF-1a) for receptor binding by displacement of biotinylated SDF-1 on Caki-CXCR4 cells in flow cytometry. This antibody exhibited medium/low potency (IC₅₀ ≥ 10 nM). In its bi-specific construction with clone 57A07, it served a functional role (US20220242958).

• SKU: ABAAb04369-34.11-BS
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04369-34.11-BS
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA, Flow Cytometry
• Isotype: VHH
• Host: Camelid