CloneID: MA-15C5
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with purified fragment D-dimer from cross linked human fibrin.
Origin Pub PMID: 1885569
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P02671
Specificity Statement: This antibody is directed against a neoantigenic determinant expressed on the human fragment D-dimer. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. At D-dimer test is done to determine if a person has any blood clotting disorder.
Application Notes (Clone): This antibody has a 1000 fold higher affinity for binding human fragment D-dimer than for human fibrinogen. It could effectively bind D-dimer from human plasma clots and can be used for thrombus imaging in an animal model in vivo (PMID: 2749602). This antibody has been used in an ELISA assay for the quantification of fragment-D dimer in plasma (PMID: 3127914).
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