CloneID: H3L2
Antigen Long Description: The original antibody is a humanized version of the parental murine monoclonal antibody.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q9NR61
Specificity Statement: The antibody is specific for DLL4.
Application Notes (Clone): The antibody retained the high affinity of the parental murine antibody to human DLL4 antigen (KD = 2.26 pM), as measured by SPR experiments. The humanized antibody bound to the DLL4 antigen on the surface of HUVEC cells, as shown by flow cytometry. Further, the antibody could block the inhibitory effect of DLL4 on the proliferation of HUVEC cells (CN105384819B).