Anti-E-selectin (7A9)

Anti-E-selectin [7A9], Recombinant, IgG kappa, Rabbit

CloneID: 7A9

Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with IL-1 activated human endothelial cells.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.

Uniprot Accession No.: P16581

Specificity Statement: The antibody recognizes the endothelial leukocyte adhesion molecule-1 (ELAM-1) protein as expressed in COS cells.

Application Notes (Clone): The F(ab')2 fragment of this antibody showed dose-dependent inhibition of cells activated with IL-1 beta, cells used were human granulocytes. The antibody binds to IL-1 activated human endothelial cells (HEC) but not significantly to normal resting HEC.

• SKU: ABAAb02952-23.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab02952-23.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA, Blocking
• Isotype: IgG kappa
• Host: Rabbit