CloneID: C8
Antigen Long Description: The original antibody was isolated from a naïve library by phage display by panning against FGFR1.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P11362
Specificity Statement: The antibody is specific for FGFR1.
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody detected FGFR1 by western blot analysis. The antibody recognized the FGFR1-GFP construct in immunofluorescence analysis on HeLa cells. The binding affinity of the original format of the antibody to FGFR1 was measured by surface plasmon resonance (Kd= 9.3 nM). The antibody was successfully employed in a sandwich ELISA (Monega et al., 2009; PMID: 19196718).
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