CloneID: 01.4B
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was raised by isolating B cells isolated from PMBCs of patients vaccinated with DS-Cav1.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human Fab format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: C3UPB8
Specificity Statement: This antibody reacts with beta3-beta4 and the base of the alpha4 helix in site V as well as residues 262–265 associated with antigenic site II.
Application Notes (Clone): The original version of this antibody was used for a neutralization assay on NCI-H28 cells and recombinant mKate-RSV subtype A. The structure of this antibody was determined using x-ray crystallography. This antibody was used for an ELISA on DS-Cav1 (Mukhamedova et al., 2022; PMID:33823129).
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