CloneID: C5
Antigen Long Description: The original antibody was raised by immunizing a mouse with human rhinovirus 14.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P03303
Specificity Statement: This antibody is specific for capsid protein VP3, NIm-III site of Human rhinovirus 14.
Application Notes (Clone): The structure of the original antibody bound to its antigen was determined using cryo-EM. Further the original antibody was used for both a preattachment neutralizing assay and a postattachment neutralization assay on HeLa-H1 cell monolayers. The antibody showed the ability to neutralize RV-B14 in both assays. The antibody was able to trigger genome release in the virus (Dong et al., 2017; PMID:28696310).
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