CloneID: VHH 17B
Antigen Long Description: The original antibody was raised by immunizing a dromedary with poliovirus type 1 Sabin strain.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P03300
Specificity Statement: This antibody is specific for the top of the VP3 protein from the genome polyprotein of the poliovirus.
Application Notes (Clone): The structure of the original antibody was determined using cryo-EM (Strauss et al., 2017; PMID:27852863). The binding strength of the original antibody to poliovirus antigens was determined using surface plasmon resonance (Thys et al., 2011; PMID:21371506).
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