CloneID: Mab243
Antigen Long Description: The original antibody was generated by immunizing mice with HLA-A201 with EBV (strain B95-8) LMP2A (CLGGLLTMV) 426-434 recombinant protein.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody is specific for the HLA-A0201/EBV-LMP2 (CLGGLLTMV) peptide complex.
Application Notes (Clone): The binding characterization of this antibody towards HLA-A02:01 EBV-LMP2A complex was done using flow cytometry. The binding of the antibody was tested against peptide pulsed HLA expressing human cell lines using flow cytometry. This antibody was capable of binding EBV LMP2 peptide (CLGGLLTMV) expressed on HLA-A0201, HLA-A0206 and HLA-A0207. This antibody was used for the immunohistochemical staining of EBV infected-HLA-A0201 positive nasopharyngeal carcinoma (NPC) biopsies (WO2015199618).
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