CloneID: SN66E3
Antigen Long Description: The original antibody was generated from the peripheral B lymphocytes from a multiparous female (SN) who had developed anti-HLA-A2 and anti-HLA-B17 Abs following two pregnancies mismatched for these HLA class I allospecificities.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This reformatted human antibody was made using the variable domain sequences of the original Human IgM format for improved compatibility with existing reagents assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P04439
Specificity Statement: The antibody specifically binds a determinant shared by human HLA-A2 and A28, but does not cross react with Aw68, or Aw69 antigens.
Application Notes (Clone): This antibody was used in the flow cytometric analysis of HLA class I antigen expression levels on Lymphoblastoid cell lines and class I deficient mutant cells (PMID: 9820600).
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