Anti-HLA-Cw6 (Cw6_4)

Anti-HLA-Cw6 [Cw6_4], Recombinant, IgG2b lambda, Mouse

CloneID: Cw6_4

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original antibody was isolated from fully synthetic human combinatorial antibody library (HuCAL) by screening against a cell-bound human lymphocyte antigen HLA-Cw6. Cw6 stable cell line was generated by transfecting human lymphoblastoid LCL 721.221 HLA class I null cell line.

Buffer Composition: PBS only.

Chimeric Use Statement: This full-length chimeric mouse antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.

Uniprot Accession No.: P10321

Specificity Statement: This antibody binds human HLA-Cw6. This antigen-presenting major histocompatibility complex class I (MHCI) molecule has an important role in reproduction and antiviral immunity.

Application Notes (Clone): The binding specificity of the scFv antibody towards human HLA-Cw6, expressed on the cell surface was done using flow cytometry. This antibody was also used for the immunoprecipitation of Cw*0602-transfected LCL721.221 cells (WO2001014558).

• SKU: ABAAb03370-3.3-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03370-3.3-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunoprecipitation, Flow Cytometry
• Isotype: IgG2b Lambda
• Host: Mouse