Anti-IL-3Ra (55A01)

Anti-IL-3Ra [55A01], Recombinant, IgG1-Fc Fusion, Human

CloneID: 55A01

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P26951

Specificity Statement: This antibody is specific for the alpha subunit of IL-3R

Application Notes (Clone): The binding of the original version of this antibody (VHH) to IL3-Ra-expressing viral lipoparticles was characterized in an ELISA (K_D 17.1 nM). In a FACS binding assay, this antibody exhibited an EC₅₀ of 8.2 nM, 11 nM, and 1.1 nM for MOLM-13, THP-1, and HEK-IL-R3a, respectively, and an IC₅₀ of 40.0 nM in competition against clone 7G3. In its bi-specific constructions with clones 14D09 and 281F12, it served as an anchor (US20220242958).

• SKU: ABAAb04371-10.159-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04371-10.159-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA, Fluorescence-Activated Cell Sorting (FACS)
• Isotype: IgG1-Fc Fusion
• Host: Human