CloneID: 55A01
Heavy Chain modification: His-tagged
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P26951
Specificity Statement: This antibody is specific for the alpha subunit of IL-3R
Application Notes (Clone): The binding of the original version of this antibody (VHH) to IL3-Ra-expressing viral lipoparticles was characterized in an ELISA (KD 17.1 nM). In a FACS binding assay, this antibody exhibited an EC50 of 8.2 nM, 11 nM, and 1.1 nM for MOLM-13, THP-1, and HEK-IL-R3a, respectively, and an IC50 of 40.0 nM in competition against clone 7G3. In its bi-specific constructions with clones 14D09 and 281F12, it served as an anchor (US20220242958).