Anti-IL12RB1 (148C09)

Anti-IL12RB1 [148C09], Recombinant, IgG1-Fc Fusion, Human

CloneID: 148C09

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P42701

Specificity Statement: This antibody is specific for human IL12RB1

Application Notes (Clone): The binding of the original version of this antibody (VHH) to IL12RB1 was characterized in an SPR (K_D 3.3 nM), ELISA (IC₅₀ 3.7 and 1.5 nM for IL-12 and IL-23, respectively), and FACS (EC₅₀ 1.3 nM). In its bi-specific constructs with Ab04387 (Anti-CD4 [3F11]), it served a functional role (US20220242958).

• SKU: ABAAb04392-10.159
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04392-10.159
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA, Super-Resolution Microscopy, Inhibition, Fluorescence-Activated Cell Sorting (FACS)
• Isotype: IgG1-Fc Fusion
• Host: Human