CloneID: 148C09
Buffer Composition: PBS only.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P42701
Specificity Statement: This antibody is specific for human IL12RB1
Application Notes (Clone): The binding of the original version of this antibody (VHH) to IL12RB1 was characterized in an SPR (KD 3.3 nM), ELISA (IC50 3.7 and 1.5 nM for IL-12 and IL-23, respectively), and FACS (EC50 1.3 nM). In its bi-specific constructs with Ab04387 (Anti-CD4 [3F11]), it served a functional role (US20220242958).