CloneID: 148C09
Heavy Chain modification: His-tagged
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P42701
Specificity Statement: This antibody is specific for human IL12RB1
Application Notes (Clone): The binding of the original version of this antibody (VHH) to IL12RB1 was characterized in an SPR (KD 3.3 nM), ELISA (IC50 3.7 and 1.5 nM for IL-12 and IL-23, respectively), and FACS (EC50 1.3 nM). In its bi-specific constructs with Ab04387 (Anti-CD4 [3F11]), it served a functional role (US20220242958).