Antigen Long Description: The original antibody was generated by immunizing Balb/c mice with INHibin-α.
Buffer Composition: PBS only.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Uniprot Accession No.: P05111
Specificity Statement: The antibody is specific for INHibin-α. Inhibin is one of the important hormones regulated by the hypothalamic-pituitary-gonadal axis system. Inhibin is a member of the TGF-β family, by reducing the transcription of the follicle-stimulating hormone gene and down-regulating the gonadotropin-releasing hormone receptor, it exerts local effects in the form of paracrine and autocrine, and inhibits the basic and receptor of the anterior pituitary gland.
Application Notes (Clone): The antibody was used to stain ovarian sex cord stromal tumor in immunohistochemical analysis (CN114075281A).