Anti-Integrin alpha 6 beta 1 (TS2/16)

Anti-Integrin alpha 6 beta 1 [TS2/16], Recombinant, IgG kappa, Rabbit

CloneID: TS2/16

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P23229; P05556

Specificity Statement: The antibody is specific for human integrin alpha 6 beta 1. It does not cross-react with mouse integrin β1.

Application Notes (Clone): The antibody immunoprecipitated the 130 kDa ß1 form of in U87MG cells. Flow cytometry analysis performed with the antibody confirmed that it could recognise ß1-A172 cells (Bartik et al., 2008; PMID: 18425328). The structure of the Fv-clasp fragment of the antibody was determined. Further, the crystal structure of the a6b1 headpiece complexed with Fv-clasp was determined (Arimori et al., 2017; PMID: 28919443). The antibody increased integrin ß1 in vitro and in vivo (Ritsma et al., 2017; PMID: 28448494)

• SKU: ABAAb03837-23.0
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03837-23.0
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunoprecipitation, Flow Cytometry, Crystallography, In Vivo Assay
• Isotype: IgG kappa
• Host: Rabbit