Anti-LAG3 (AbAbLAG3)

Anti-LAG3 [AbAbLAG3], Recombinant, IgG1 kappa, Human

CloneID: AbAbLAG3

Antigen Long Description: The original antibody was generated by immunizing transgenic HuMab or KM mice with recombinant human LAG-3 protein.

Buffer Composition: PBS only.

Uniprot Accession No.: P18627

Specificity Statement: The antibody is specific for LAG3. Lymphocyte activation gene 3 protein is an inhibitory receptor on antigen activated T-cells. It delivers inhibitory signals upon binding to ligands, such as FGL1.

Application Notes (Clone): The binding characterization of this antibody to human LAG3-Fc fusion protein was done using ELISA. The original human IgG antibody was reported to bind human LAG-3 in the sub picomolar range. This antibody was effective in inhibiting the binding of LAG3 to MHC class II molecules in an in vitro binding assay. In the antigen-specific T cell response assay, this antibody can stimulate the production of IL-2 (CN109748963).

• SKU: ABAAb03953-10.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03953-10.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA, Inhibition
• Isotype: IgG1 kappa
• Host: Human