CloneID: 26-1
Antigen Long Description: The original antibody was originated by immunizing rabbits with an LgR5 extracellular domain (ECD) huFc.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: O75473
Specificity Statement: The antibody is specific for human LgR5. The antibody binds an epitope in the region of amino acids 22 to 322 of human LgR5.
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The original format of the antibody could recognise human LgR5 expressed in 293 cells by FACS. The antibody detected LgR5 in different colon cancer cell lines (SW403, LS180, SW948, CACO-2, T84, KM-12, C2BBel, SW1463, SK-CO-1, LOVO, DLD-1, SW620) by immunohistochemistry (US20190248889).