CloneID: H16.U4
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was raised by immunizing a BALB/c mouse with HPV-16 or HPV-18 L1 VLPs.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted mouse IgG2a Fc Silent™ antibody, based on the original mouse IgG2a format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P03101
Specificity Statement: This antibody is specific for amino acids 427 to 445 of the C-terminal arm of L1.
Application Notes (Clone): The original antibody was used for an ELISA on intact papillomavirus and virus like particles contained L1 protein of different papillomavirus genotypes, and on L1 protein (Guan et al., 2015; PMID:26401038), on HPV quasivirus (Guan et al., 2017; PMID:29211035), and on HPV virus like particles (Carter et al., 2003; PMID:14557648). Further this antibody was used for a western blot on L1 protein (Christensen et al., 1996; PMID:8806551). The structure of this antibody was determined using cryo-EM (Guan et al., 2015; PMID:26401038, Guan et al., 2017; PMID:29211035).
English
Deutsch
