CloneID: Ab2000
Antigen Long Description: The original antibody was generated by phage display method. A phage display library was screened against the extracellular domain of human and/or mouse MerTK.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q12866
Specificity Statement: The antibody specifically binds to human MerTK.
Application Notes (Clone): The specificity of the IgG1 format of the antibody was confirmed by ELISA analysis. The antibody bound to cellularly expressed full length human MerTK in a dose responsive manner, with EC50 values in the picomolar to nanomolar range, as determined by FACS. The antibody inhibited Gas6 binding to hMerTK in a dose responsive manner, with an IC50 of 1 nM (WO2019084307A1).
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