CloneID: 3K11
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing Balb/c mice with two morphine derivative 3-O-carboxymethyl ester, conjugated to BSA.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds morphine and also recognizes the 3-O-carboxymethyl ester of morphine. Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (Papaver somniferum). It is considered the classic opioid analgesic, most commonly used in pain management, morphine provides major relief to patients afflicted with pain. It is a non-synthetic narcotic with a high potential for abuse.
Application Notes (Clone): This antibody binds morphine with a binding affinity of Kd = 61nM. The binding characterization of this antibody to the 3-O-carboxymethyl ester of morphine was done using ELISA (PMID: 32219918).
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