Anti-Bcl-3 (ham150-3.5)

Anti-Bcl-3 [ham150-3.5], Recombinant, IgG1 lambda, Mouse

CloneID: ham150-3.5

Antigen Long Description: The original antibody was generated from a hamster immunized with mouse BCL-3.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original Hamster IgG format for improved compatibility with existing reagents assays and techniques.

Uniprot Accession No.: Q9Z2F6

Specificity Statement: The antibody is specific for BCL-3. B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells.

Application Notes (Clone): The specificity of the original format of the antibody for mBcl-3 was confirmed by ELISA analysis. The antibody detected mBcl-3 and human Bcl-3 by western blot (Bassetti et al., 2009; PMID: 19208752).

• SKU: ABAAb03543-1.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03543-1.1-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Recombinant
• Application: Western Blotting, ELISA, Flow Cytometry
• Isotype: IgG1 lambda
• Host: Mouse