CloneID: CA782
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing mice with PD-L1, followed by antibody library construction and phage display-based selection against PD-L1.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: Q9NZQ7
Specificity Statement: The original antibody is specific for PD-L1.
Application Notes (Clone): The binding affinity of the antibody to PD-L1 was measured by surface plasmon resonance. The antibody had good activity in blocking the binding of PD-L1 to PD-1 and PD-L1 to B7-1 is shown by ELISA analysis.