CloneID: 10G6D9E8
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing mice with PLAP.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P05187
Specificity Statement: The antibody is specific for PLAP. PLAP is an allosteric enzyme that in humans is encoded by the ALPP gene.
Application Notes (Clone): The antibody specifically detected PLAP by Western blot analysis. The antibody 10G6D9E8 and the commercial antibody 8A9 were used to stain germ cell tumor. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 10G6D9E8 was higher than the commercial antibody. The antibody and the commercially available antibody 8A9 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN114014933A).
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