CloneID: sFab H3
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was raised from a phage display library.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human Fab format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: Q03039
Specificity Statement: This antibody is specific for interferon(IFN)-inhibitory-domain (VP35 IID) of Lake Victoria marburgvirus.
Application Notes (Clone): The original antibody was used for an ELISA on mVP35 IID protein. Further this antibody was used in hydrogen deuterium exchange mass spectrometry on mVP35 IID. Finally the structure of this antibody was determined using x-ray crystallography (Amatya et al., 2019; PMID:31120240).
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