CloneID: 42C07
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with necrotic strains of Potato virus Y (PVY-T).
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P22602
Specificity Statement: This antibody binds the coat protein of the Potato virus Y (PVY). Potato virus Y is a monopartite, single stranded RNA virus, plant pathogen that infects mainly Solanaceous plants including, potato, tomato, pepper, tobacco and eggplant. There are multiple strains of the virus including the common strain, PVYO, which causes mosaic symptoms in most hosts. The necrotic strains PVYN and PVYNTN both cause a veinal necrosis on tobacco; PVYNTN also causes a tuber necrosis in certain potato varieties. This necrosis is referred to as potato tubers necrotic ringspot disease (PTNRD). In general, the necrotic strains tend to cause a more mild mosaic symptom than PVYO in potato. PVY is transmitted in a non-persistent manner by aphids.
Application Notes (Clone): This antibody reacted with both PVY-O and PVY-T13 strains of Potato virus Y in an ELISA, microprecipitin and western blots (Oshima et al., 1994). This antibody was also used in a double antibody sandwich ELISA for detection of Potato virus Y in the leaves from plants with necrotic tubers symptoms (PMID: 30831903).