Antigen Long Description: The original mouse antibody was generated by immunizing mice with human BNP peptide 5-13 (VQGSGAFGR) conjugated with BSA.
Buffer Composition: PBS only.
Uniprot Accession No.: P16860
Specificity Statement: This antibody binds B-type natriuretic peptide (BNP) 5‐13 (VQGSGAFGR). BNP is a naturally secreted cardiac regulatory hormone that influences blood pressure and vascular water retention in human physiology. The plasma BNP concentration is a clinically recognized biomarker for various cardiovascular diseases.
Application Notes (Clone): This antibody can be used for the detection of human BNP using ELISA (PMID: 18606632). This antibody when crosslinked to POROS XL ID resin can also be used in the immunoprecipitation of BNP from plasma samples of patients with chronic heart failure (PMID: 16750161).