Anti-PVRIG (334MXX)

Anti-PVRIG [334MXX], Recombinant, IgG1 kappa, Human

CloneID: 334MXX

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original antibody was generated by immunizing mice with human PVRIG linked to a human IgG Fc region.

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: Q6DKI7

Specificity Statement: The antibody specifically binds to human PVRIG.

Application Notes (Clone): The original version and the humanized version antibody were able to inhibit PVRIG activity and signaling. The binding of the original format or the humanized version of the antibody to PVRIG decreased PVRL2 activity, as shown by FACS analysis on HEK-293T cells transfected with hPVRIG (WO2018017864A3).

• SKU: ABAAb03798-10.3
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03798-10.3
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Fluorescence-Activated Cell Sorting (FACS)
• Isotype: IgG1 kappa
• Host: Human