Anti-Siglec-7 (Siglec7-01)

Anti-Siglec-7 [Siglec7-01], Recombinant, IgG lambda, Rabbit

CloneID: Siglec7-01

Antigen Long Description: The original antibody was isolated from a human Fab antibody library by panning against human siglec-7.

Buffer Composition: PBS only.

Uniprot Accession No.: Q9Y286

Specificity Statement: This antibody binds human siglec-7. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid.

Application Notes (Clone): This antibody can bind recombinant human siglec-7 protein in an ELISA and western blot. The binding affinity of the IgG antibody for human siglec-7 was reported to be Kd= 71.5 nM. In vitro, this antibody was capable of enhancing killing effect of NK cells on tumor cells (CN106831989).

• SKU: ABAAb03725-23.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03725-23.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Isotype: IgG lambda
• Host: Rabbit