CloneID: #3
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing Balb/c mice with SM03.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG2a format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P20273
Specificity Statement: The antibody is an anti-idiotypic antibody for human CD22. The antibody binds to RFB4, SM03 and SM06.
Application Notes (Clone): The antibody could adsorb RFB4, SM03 and SM06 (murine, chimeric and humanized CD22 antibodies) by ELISA analysis. The antibody could effectively inhibit the human CD22 antibody SM03 from adsorbing CD22 antigen on the surface of Raji cells as shown by flow cytometry analysis. The antibody was used as a solid-phase capture antibody by ELISA analysis (CN103588882A).
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