CloneID: scFvF7
Heavy Chain modification: ScFv
Antigen Long Description: The original antibody was isolated from a yeast display library by two rounds of screening against Sweet potato leaf curl virus (SPLCV).
Origin Pub PMID: 32415170
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human scFv antibody, based on the original human scFv format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: E5G5X2
Specificity Statement: This antibody recognizes and binds the Sweet potato leaf curl virus (SPLCV), which causes yield losses in sweet potato cultivation. The sweet potato leaf curl virus, a member of the genus Begomovirus, is transmitted by the whitefly (Bemisia tabaci Genn.), which is the only natural vector. SPLCV causes symptoms including upward leaf curling in young stage and is responsible for declining yields around the world.
Application Notes (Clone): The binding characterization of this antibody for sweet potato leaf curl virus (SPLCV) coat protein was done using ELISA. This antibody can also bind SPLCV-infected sweet potato samples of leaves and infected phloem tissue. This antibody was also expressed as a bivalent scFv protein to increase antigen-binding affinity (PMID: 32415170).
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