Anti-TIGIT (1F4)

Anti-TIGIT [1F4], Recombinant, IgG1 kappa, Human

CloneID: 1F4

Antigen Long Description: The original antibody was generated by immunizing hamsters with murine TIGIT-Fc fusion protein.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: Q495A1

Specificity Statement: The antibody is specific for human TIGIT. TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

• SKU: ABAAb03858-10.0
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03858-10.0
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Recombinant
• Isotype: IgG1 kappa
• Host: Human