Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: Q9QX05
Specificity Statement: This antibody binds rat toll like receptor 4.
Application Notes (Clone): This antibody was reported to completely inhibit lipopolysaccharide-induced interleukin-6 secretion in vitro. The binding of this antibody to rat cells stable expressing TLR4/MD2 was done using ELISA (PMID: 33290148).