Anti-VEGFR2 (B1A1)

Anti-VEGFR2 [B1A1], Recombinant, IgG lambda, Rabbit

CloneID: B1A1

Antigen Long Description: The original antibody was isolated by panning a phage display library against VEGFR2.

Buffer Composition: PBS only.

Uniprot Accession No.: P35968

Specificity Statement: The antibody is specific for VEGFR2.

Application Notes (Clone): The bispecific antibody (A1-A8)-LALA associated with either VEGFR2 or PDLl fast and stayed on either VEGFR2 or PDLl long (KD values of BsAb (A1-A8) were about 200 pM and 3.2 pM for the hVEGFR2 and hPDLl). A cytokine secretion assay was carried out with the bispecific antibody and B1A1. The results indicate that in the present of BsAb (A1-A8)-LALA, the secretion of cytokine IL2 and INFy in PBMC when stimulated by SEB was higher than the control antibody B1A1, demonstrating that BsAb (A1-A8)-LALA retains the potency of its parental antibody B1A1 (against VEGFR2) and dsD7A8-LALA (against PDL1) (EP3411068A4).

• SKU: ABAAb04124-23.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04124-23.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Surface Plasmon Resonance (SPR)
• Isotype: IgG lambda
• Host: Rabbit