CloneID: RV202
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing a BALB/c mouse with a cytoskeletal vimentin extract of calf lens.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P08670
Specificity Statement: The antibody reacts exclusively with vimentin, which is expressed in mesenchymal cells and mesenchymal derived tumors e.g. lymphoma, sarcoma and melanoma.
Application Notes (Clone): The antibody detected vimentin by western blot analysis. This antibody was used for vimentin detection on rabbit embryo, dermatome, myotome (adjacent abdominal wall) and the genital ridge (comprising mesonephric blastema and mesonephric duct) by immunohistochemistry (Viebahn et al., 1988; PMID: 2460241). The original antibody detected vimentin on HeLa cells transfected with pRSVDes by immunohistochemistry (Raats et al., 1990; PMID: 1699950).
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