CloneID: JG7
Heavy Chain modification: ScFv
Antigen Long Description: The original antibody was generated by selecting antibody fragments using phage display technology, where two phage display libraries were amplified and used to screen for binding to von Willebrand factor propeptide (VWFpp) displayed on yeast cells.
Origin Pub PMID: 29992156
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted human scFv antibody, based on the original human scFv format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody is specific for VWF propeptide (VWFpp) and not to the yeast used for the expression of the propeptides.
Application Notes (Clone): This antibody's original format (scFv) was used in a sandwich ELISA to determine the VWF propeptide levels in plasma and showed a higher binding affinity for VWFpp in plasma at especially lower plasma concentrations (Meiring et al., 2018; PMID: 29992156).
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