ARN-3236, CAS 1613710-01-2

Product Description: ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), with IC50s of [1][2].

Applications: Cancer-Kinase/protease

Formula: C19H16N2O2S

References: [1]Lombardi MS, et al. SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype. J Leukoc Biol. 2016 May;99(5):711-21./[2]Zhou J, et al. A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts. Clin Cancer Res. 2017 Apr 15;23(8):1945-1954.

CAS Number: 1613710-01-2

Molecular Weight: 336.41

Compound Purity: 99.66

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Salt-inducible Kinase (SIK)

• SKU: MEXHY-120856-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120856-25
• Package Unit: 25 mg
• Quantity Unit: STK