AZ12799734, CAS 1117684-36-2

Product Description: AZ12799734 is a selective, orally active TGFBR1 kinase inhibitor with an IC50 of 47 nM. AZ12799734 is also a pan BMP and TGFβ inhibitor[1].

Applications: Neuroscience-Neuromodulation

Formula: C18H18N4O3S

References: [1]Spender LC, et al. Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor β Superfamily Type 1 Receptors. Mol Pharmacol. 2019 Feb;95(2):222-234./[2]Anderton MJ, et al. Induction of heart valve lesions by small-molecule ALK5 inhibitors. Toxicol Pathol. 2011 Oct;39(6):916-24.

CAS Number: 1117684-36-2

Molecular Weight: 370.43

Compound Purity: 98.07

Research Area: Cardiovascular Disease

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: TGF-β Receptor

• SKU: MEXHY-123900-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123900-100
• Package Unit: 100 mg
• Quantity Unit: STK