AZD8542, CAS 1126366-36-6

Product Description: AZD8542 is an antagonist of Smoothened (SMO), playing an important role in oncology. AZD8542 is a Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment[1][2].

Applications: Cancer-programmed cell death

Formula: C25H24N4O2

References: [1]Rosa F. Hwang, INHIBITION OF THE HEDGEHOG PATHWAY TARGETS THE TUMOR-ASSOCIATED STROMA IN PANCREATIC CANCER. Mol Cancer Res. 2012 Sep; 10(9): 1147–1157./[2]Dakin Leslie, et al. Preparation of amide compounds containing heterocycle moiety as hedgehog pathway inhibitors. World Intellectual Property Organization, WO2009027746 A1

CAS Number: 1126366-36-6

Molecular Weight: 412.48

Compound Purity: 99.49

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Hedgehog;Smo

• SKU: MEXHY-120499-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120499-5
• Package Unit: 5 mg
• Quantity Unit: STK