Shelf life (days): 1460.0
Formulation: A solid
Formal Name: L-alanyl-L-a-glutamyl-L-lysyl-L-lysyl-L-a-aspartyl-L-a-glutamylglycyl-L-prolyl-L-tyrosyl-L-arginyl-L-methionyl-L-a-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-seryl-L-prolyl-L-prolyl-L-lysyl-L-aspartic acid
Amino Acids: AEKKDEGPYRMEHFRWGSPPKD-OH
Purity: ≥98%
Formula Markup: C118H174N34O35S
Formula Weight: 2660.9
CAS Number: 17908-57-5
Notes: β-Melanocyte-stimulating hormone (β-MSH) is a peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland.{69880,69881} It selectively binds to melanocortin receptor 1 (MC1R) over MC3R, MC4R, and MC5R (Kis = 0.89, 10.64, 8.18, and 76.9 nM, respectively).{69882} β-MSH (1 µM) induces lipolysis in isolated rabbit adipocytes.{69881} It increases plasma levels of glucagon, insulin, and free fatty acids in fed or fasted rabbits when administered at a dose of 45 µg/animal.{69883} Cerebrospinal fluid (CSF) levels of β-MSH are increased in patients with restless legs syndrome with painful symptoms.{69884}
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