Bayer 18, CAS 1251752-12-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-(1,1-dimethylethyl)-N'-[3-[[5-fluoro-4-[(2-hydroxy-1,1-dimethylethyl)amino]-2-pyrimidinyl]amino]phenyl]-urea

Purity: ≥98%

Formula Markup: C19H27FN6O2

Formula Weight: 390.5

CAS Number: 1251752-12-1

Notes: Bayer 18 is a tyrosine kinase 2 (TYK2) inhibitor (IC50 = 18.7 nM).{69842} It is selective for TYK2 over JAK2, cyclin-dependent kinase 2 (Cdk2), and VEGFR2 (IC50s = 2,000, 1,790, and 3,520 nM, respectively).

• SKU: CAY41124-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41124-10
• Package Unit: 10 mg
• Quantity Unit: STK