BBT594, CAS 882405-89-2

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 5-[[6-(acetylamino)-4-pyrimidinyl]oxy]-2,3-dihydro-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-1H-indole-1-carboxamide

Purity: ≥98%

Formula Markup: C28H30F3N7O3

Formula Weight: 569.6

CAS Number: 882405-89-2

Notes: BBT594 is an inhibitor of Bcr-AblT315I (IC50 = 44 nM), a form of the Bcr-Abl fusion protein containing a tyrosine-to-isoleucine substitution at position 315.{72409} It decreases proliferation in mouse Ba/F3 hematopoietic cells expressing Bcr-AblT315I (GI50 = 117 nM). BBT594 (1 or 5 µM) also inhibits phosphorylation of Jak2 and Stat5 in Ba/F3 cells.{49912}

• SKU: CAY41359-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41359-5
• Package Unit: 5 mg
• Quantity Unit: STK