Product Description: Berberrubine chloride is an orally active metabolite of berberine. Berberrubine chloride alleviates mucosal lesions and inflammation in mouse colitis models. Berberrubine chloride has anti-inflammatory, anti-tumor, and antiviral activities[1][1][3].
Applications: COVID-19-immunoregulation
Formula: C19H16ClNO4
References: [1]Yu XT, et al. Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice. PLoS One. 2018 Mar 14;13(3):e0194069./[2]Lo CY, et al. Synthesis and anticancer activity of a novel series of 9-O-substituted berberine derivatives: a lipophilic substitute role. Bioorg Med Chem Lett. 2013 Jan 1;23(1):305-9./[3]Bodiwala HS, et al. Synthesis of 9-substituted derivatives of berberine as anti-HIV agents. Eur J Med Chem. 2011 Apr;46(4):1045-9.
CAS Number: 15401-69-1
Molecular Weight: 357.79
Compound Purity: 99.28
Research Area: Cancer; Infection; Inflammation/Immunology
Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)/Ethanol : 2 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Drug Metabolite;HIV;Interleukin Related
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