Clone Name: HL4320
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody was raised against human beta 2 Adrenergic Receptor Intracellular domain.
Form: Liquid
Buffer (with preservative): PBS, no Preservative.
Concentration: batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
Uniprot ID: P07550
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the Intracellular domain of human beta 2 Adrenergic Receptor. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: adrenoceptor beta 2
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