Braftide, CAS 2411851-64-2

Braftide, CAS 2411851-64-2
SKU
TGMTP2695-10mg
Packaging Unit
10 mg
Manufacturer
TargetMol Chemicals

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Description: Braftide is an allosteric inhibitor of BRAF kinase that exerts its effect by targeting the surface of BRAF kinase dimers, thereby preventing their formation. It inhibits both wild-type BRAF and oncogenic BRAFG469A, with IC50 values of 364 nM and 172 nM, respectively. When combined with the TAT sequence, Braftide can suppress the MAPK signaling pathway, inhibiting the proliferation of KRAS-mutant tumor cells, with EC50 values of 7.1 μM for HCT116 and 6.6 μM for HCT-15.

CAS Number: 2411851-64-2

Formula: C57H94N16O13S

Molecular Weight: 1243,52
More Information
SKU TGMTP2695-10mg
Manufacturer TargetMol Chemicals
Manufacturer SKU TP2695-10mg
Package Unit 10 mg
Quantity Unit STK
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